This program requires a member to have a trial of a maximally tolerated statin therapy and ezetimibe prior to coverage for Nexletol or Nexlizet. Nexlizet works to lower your cholesterol in two ways: * An enzyme is a protein that speeds up the chemical processes in your body. Consumer; Professional; FAQ; Note: This document contains side effect information about bempedoic acid / ezetimibe. If it does pass into breast milk, the drug may cause serious side effects in a child who is breastfed. This is because it can build up in the arteries and lead to angina (chest pain) or a heart attack. Examples of these drugs include fibrate drugs and bile acid sequestrants. However, due to stock shortages and other unknown variables we cannot provide any guarantee. See this article to learn more about how grapefruit may interact with medications. You may pay as little as $10 per month with the NEXLIZET Co-Pay Card. Nexlizet (bempedoic acid/ezetimibe) is a member of the antihyperlipidemic combinations drug class and is commonly used for High Cholesterol - Familial Heterozygous. You save … * For more information about the possible side effects of Nexlizet, see the “Nexlizet side effects” section above. No, Nexlizet won’t cure high levels of low-density lipoprotein (LDL) cholesterol. … NEXLIZET is the second commercially available product from Esperion. It’s not currently available in generic form. Contact program for details. But this side effect could affect any tendon in the body. Valid at all major chains including Walgreens, CVS Pharmacy, Target, WalMart Pharmacy, Duane Reade and 65,000 pharmacies nationwide. Select one or more newsletters to continue. If you’re taking cyclosporine, talk with your doctor about whether it’s safe for you to take Nexlizet. In this article learn about the vegan diet, the Mediterranean diet, and the TLC diet. This will help your body maintain stable levels of the drug. Keep Nexlizet tablets in their original container and store them away from light. Generic Name: bempedoic acid / ezetimibe. To help make sure that you don’t miss a dose, try using a medication reminder. Note: Some of the drugs listed here are used off-label to treat these specific conditions. Nexlizet is FDA-approved to help reduce low-density lipoprotein (LDL) cholesterol in adults. Estimated cash price $395.99. Some people may have troublesome side effects from statins that prevent them from being able to take these drugs. Off-label drug use is when an FDA-approved drug is used for a purpose other than what it’s approved for. If you no longer need to take Nexlizet and have leftover medication, it’s important to dispose of it safely. Here, we look at how Nexlizet and Nexletol are alike and different. If you and your doctor determine that Nexlizet is safe and effective for you, you’ll likely take it long term. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. NEXLIZET Savings, Coupons and Information. Nexlizet has been found effective in helping reduce LDL cholesterol in adults. Lowering your cholesterol: How long does it take? (Ezetimibe is one of the active drugs in Nexlizet.) Nexlizet (bempedoic acid and ezetimibe) Tablet, *See Additional Information section below. The maker of the drug, Esperion Therapeutics, has reported that the wholesale acquisition price of Nexletol and Nexlizet will be roughly $10 a pill, or approximately $3,650 per year… Nexletol or Nexlizet will be approved based on both of the following criteria: a. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Talk with your doctor or pharmacist if you have any questions about taking a statin with Nexlizet. Bempedoic acid is one of the active ingredients in Nexlizet. Both Nexlizet and statins work by preventing your liver from making new cholesterol. We comply with the HONcode standard for trustworthy health information -, Drug class: antihyperlipidemic combinations, Here are 10 ways to save money on prescription drugs, FDA Approved Diagnosis - See Program Website for Details. The drug can be taken with or without food. Cholesterol is made in your body and can also be found in many foods, such as eggs, cheese, and meat. References 1. And high levels of uric acid can lead to gout (sudden, painful swelling in the joints). HeFH is an inherited condition that causes high cholesterol. It’s typically used in combination with a low cholesterol diet and a statin drug. If you’re prescribed these drugs after you’ve started Nexlizet, tell your doctor that as well. Nexlizet can interact with several other medications. LDL cholesterol is sometimes called “bad” cholesterol. Methylprednisolone (Medrol) is an example of a corticosteroid. But it isn’t known if Nexlizet may affect these risks. But you should still check with your doctor or pharmacist before using any of these products while taking Nexlizet. If you’re interested in finding an alternative to Nexlizet, talk with your doctor. Serious side effects from Nexlizet aren’t common, but they can occur. Prices are for cash paying customers only and are not valid with … It’s approved for this use in adults with heart disease or heterozygous familial hypercholesterolemia (HeFH), an inherited condition that causes high cholesterol. Under the terms of the agreement, Esperion will grant Otsuka exclusive rights to NEXLETOL and NEXLIZET tablet development and commercialization in Japan. It is used with other cholesterol -lowering drugs. Nexlizet in pediatric patients less than 18 years of age have not been established (1-2). If you have questions about using Nexlizet with fibrate drugs, talk with your doctor. In 2020, the Food and Drug Administration (FDA) approved Nexlizet to help reduce LDL cholesterol in adults. This can increase your risk for side effects from either medication.*. If you have unused medication that has gone past the expiration date, ask your pharmacist if you can still use it. Nexlizet is a brand-name prescription drug. Nexlizet contains the active drugs bempedoic acid and ezetimibe. Nexlizet is approved to help reduce low-density lipoprotein (LDL) cholesterol* when used alongside a low cholesterol diet and a statin. Examples of bile acid sequestrants include cholestyramine (Prevalite) and colesevelam (Welchol). Nexletol and Nexlizet will be sold at a wholesale acquisition cost of $10 per day, an Esperion spokesman said, a price the drugmaker said was far below … Nexlizet isn’t available in a generic form. In the study, LDL (“bad”) cholesterol levels decreased by an average of: LDL cholesterol increased by an average of 2% in people who used a placebo. You can also ask your pharmacist for information about how to dispose of your medication. Nexlizet may be available through a mail-order pharmacy. A tendon rupture (a torn tendon) can happen while taking Nexlizet. Nexlizet is used along with diet and other lipid-lowering medicines in the treatment of adults with: heterozygous familial hypercholesterolemia (HeFH) which is an inherited condition that causes high levels of “bad” cholesterol (LDL), known heart disease who need additional lowering of “bad” cholesterol (LDL-C) levels. Nexlizet shouldn’t be taken with certain drugs in the fibrate drug class. They can recommend treatments that may help reduce your muscle spasms. You should store Nexlizet tablets with this packet inside the container. But clinical studies haven’t shown any negative effects of Nexlizet on the kidneys. Yes, there are other cholesterol-lowering drugs that are safe to use with Nexlizet. But statins work by blocking a different enzyme, called HMG-CoA reductase. Nexlizet may also be used off-label for other conditions. Estimated cash price $410.69 . But some people may have troublesome side effects from statins that prevent them from being able to take these drugs. Symptoms of gallstones may include pain in the back, the shoulder, or the right side of the body (below the ribs). Here’s some detail on certain side effects this drug may cause. And don’t throw away the packet that helps keep your medication dry. In the Post-Donut Hole (also called Catastrophic Coverage) stage, Medicare will cover most of your drug costs. If you’re interested in this option, check with your doctor or insurance company. Examples of drugs that can raise your risk for a tendon rupture if taken with Nexlizet include corticosteroids and fluoroquinolones (a type of antibiotic). Ezetimibe belongs to a group of drugs called cholesterol absorption inhibitors. You may wonder how Nexlizet compares with other medications that are prescribed for similar uses. Warning. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. In the clinical studies involving bempedoic acid and a placebo, gout occurred in: You’ll likely have your levels of uric acid monitored while you’re taking Nexlizet. What should my cholesterol level be at my age? Examples of bile acid sequestrants include cholestyramine (Prevalite) and colesevelam (Welchol). But be sure to take the dosage your doctor prescribes for you. The cost for Nexlizet oral tablet (180 mg-10 mg) is around $8 for a supply of 90 tablets, depending on the pharmacy you visit. For more information and to find out if you’re eligible, call 855-699-8814 or visit the manufacturer’s website. Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Nexlizet Side Effects. Some Medicare plans may help cover the cost of mail-order medications. But there are limitations to using Nexlizet with certain cholesterol-lowering drugs. But Nexlizet may interact with two specific statins: simvastatin (Zocor) and pravastatin (Pravachol). We'll show you prices without insurance, including any Amazon … You save $62.10. For those that need NEXLIZET or NEXLETOL, Esperion’s mission is to considerably reduce cost as a burden for patients as they strive to achieve their long-term LDL-C goals. Nexlizet is typically taken with statin drugs to help reduce low-density lipoprotein (LDL) cholesterol. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional, Nexlizet expiration, storage, and disposal, Scientists call for ‘pan-virus vaccines’ to prevent next pandemic, Diabetes drug significantly cuts body weight in adults with obesity, Noninvasive probe monitors health of 'friendly' gut bacteria, Lockdown may have boosted well-being for some. It’s available in one strength: 180 milligrams (mg) of bempedoic acid/10 mg of ezetimibe. Other drugs are available that can treat your condition. Nexlizet (bempedoic acid/ezetimibe) is a prescription tablet used to lower LDL (‘bad’) cholesterol in certain people. The safety and effectiveness of Nexletol and Nexlizet in pediatric patients less than 18 years of age have not been established (1-2). Different interactions can cause different effects. Nexlizet is typically used with statin drugs to help reduce LDL cholesterol. For more information on a low cholesterol diet to follow while you take Nexlizet, talk with your doctor. If you have questions about using Nexlizet with other cholesterol-lowering drugs, talk with your doctor or pharmacist. It’s used in combination with a low cholesterol diet and a statin drug. What are the common themes of cholesterol-cutting diets? * For this purpose, these drugs can be used in adults with either of the following conditions: These drugs should be used along with a low cholesterol diet and a statin drug. Generics usually cost less than brand-name drugs. You save $69.09. Medscape - Hyperlipidemia dosing for Nexlizet (bempedoic acid/ezetimibe), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Warnings and Precautions: Hyperuricemia: Bempedoic acid, a component of NEXLETOL and NEXLIZET, may increase blood uric acid levels. In the Donut Hole (also called the Coverage Gap) stage, you’ll pay more for your prescriptions. Both drugs were approved for patients who have reached their maximum statin tolerance, the company said. If they do, they may prescribe Nexlizet so that you can take bempedoic acid and ezetimibe together in a single pill. But based on the way Nexlizet works in your body, it may not be safe to take while pregnant. People bothered by statin side effects may use Nexlizet with other drugs that reduce LDL cholesterol instead of statins. This may prevent your body from absorbing Nexlizet, which could make it less effective in treating your condition. It also helps prevent your small intestine from absorbing cholesterol. And levofloxacin (Levaquin) is an example of a fluoroquinolone. If you don’t have insurance, you can ask your doctor or pharmacist about online pharmacy options. Please note: This is a drug discount program, not an insurance plan. They can give you tips on how to deal with any side effects that may be bothersome. KROGER. – First-Ever Non-Statin Combination Medicine, Providing 38 Percent Mean LDL-C Lowering – – Esperion Aims to Set New Industry Standard by Pricing NEXLIZET for Patient. For those that need NEXLIZET or NEXLETOL, Esperion’s mission is to considerably reduce cost as a burden for patients as they strive to achieve their long-term LDL-C goals. For those that need NEXLIZET or NEXLETOL, Esperion’s mission is to considerably reduce cost as a burden for patients as they strive to achieve their long-term LDL-C goals. Statins also help lower the risk of heart problems and death related to high cholesterol. Eating a lot of high cholesterol foods or not getting enough exercise can also raise cholesterol levels. HeFH is an inherited condition that causes high cholesterol. * Then, they’ll monitor whether the drug is working for you and whether you experience any side effects.† Your doctor may stop your Nexlizet treatment if it isn’t safe or effective for you.
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